HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,5,6,7-Tetrahydro-1-benzothiophen-4-amine → N-(4,5,6,7-Tetrahydro-1-benzothiophen-4-yl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,5,6,7-Tetrahydro-1-benzothiophen-4-amine | HCID 4216372 | — |
| Reactant | N-Benzoyl-L-glutamic acid | HCID 11345724 | — |
| Product | N-(4,5,6,7-Tetrahydro-1-benzothiophen-4-yl)urea | HCID 13036998 | — |
Reaction Steps
Similarly, the salt of (+)-4,5,6,7-tetrahydrobenzo[b]thiophen-4-amine and (S)-(-)-N-benzoyl glutamic acid is treated in the above manner to afford (+)-4,5,6,7-tetrahydrobenzo[b]thien-4-ylurea, melting point 218° C. to 220° C.; [α]589 25 +60° , [α]436 +149.8° , [α]365 +272.5°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04036979 |
| Source dataset | uspto-grants-1977_07 |
| ORD ID | ord-722447fa31b04ff58de6c4af1a5a71f2 |
| Source note | uspto-grants-1977_07 |