HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 5-Iodo-4,5,6,7-tetrahydrobenzo[b]thien-4-ylurea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Iodine | HCID 807 | — |
| Reactant | 6,7-Dihydrobenzo[b]thiophene | HCID 20348965 | — |
| Reactant | 5-Iodo-4,5,6,7-tetrahydrobenzo[b]-thien-4-yl isocyanate | HCID 20348985 | — |
| Catalyst | HCID 178521675 | HCID 178521675 | — |
| Product | 5-Iodo-4,5,6,7-tetrahydrobenzo[b]thien-4-ylurea | HCID 20348968 | — |
Reaction Steps
A sample of 6,7-dihydrobenzo[b]thiophene is stirred with silver isocyanate and iodine as described in Example 39 and the resulting product, 5-iodo-4,5,6,7-tetrahydrobenzo[b]-thien-4-yl isocyanate is treated with concentrated ammonia solution to afford 5-iodo-4,5,6,7-tetrahydrobenzo[b]thien-4-ylurea. This latter product is then reduced in the manner described in Example 40 to afford 4,5,6,7-tetrahydrobenzo[b]-thien-4-ylurea.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04036979 |
| Source dataset | uspto-grants-1977_07 |
| ORD ID | ord-ef51a6b4959c4f5a9595ee93383637f7 |
| Source note | uspto-grants-1977_07 |