HCID 12510270, compound → HCID 12510278, compound

Participants

Reaction Steps

13.4 g of 4-(1-adamantyloxy)-2-fluoronitrobenzene (approximately 80% pure; 0.037 mole) in ethyl acetate solution was hydrogenated for two hours over platinum (from 1.0 g of PtO2). The catalyst was filtered and the solvent was evaporated to give 13.1 g of white solid, which was purified by two recrystallizations from CH2Cl2 -Skellysolve B, affording a pink solid, m.p. 152.0-154.0. The NMR spectrum of this material was consistent with the assigned structure.

Provenance & Evidence