Piperidine → HCID 20312200, compound

Participants

Reaction Steps

A mixture of N-(n-decyl)cyanoacetamide (93.4 g., 0.417 mole), 2.4-pentanedione (41.7 g., 0.417 mole), piperidine (8 ml.) and 2 B-ethanol (500 ml.) is stirred and refluxed for 17 hours. The mixture is cooled in an ice bath and the solid which crystallizes out is collected by filtration to give 1-(n-decyl)-3-cyano-4,6-dimethylpyrid-2-one, 95.2 g. mp. 82°-83° C.

Provenance & Evidence