Iodoethane → HCID 86734967, compound

Participants

Reaction Steps

22.1 g. of 4-hydroxy-2-methyl-2H-pyrazolo[3,4-b]pyridine-5-carboxylic acid, ethyl ester (0.1 mol.), 17.1 g. of ethyl iodide and 21 g. of potassium carbonate (0.15 mol.) are stirred together in 200 ml. of dimethylformamide at 80° for 12 hours. The inorganic precipitate is filtered off and the filtrate evaporated to dryness. Recrystallization of the residue with ethyl acetate yields 18.2 g. of 7-ethyl-4,7-dihydro-2-methyl-4-oxo-2H-pyrazolo[3,4-b]pyridine-5-carboxylic acid, ethyl ester, yield (73%); m.p. 170°-172°.

Provenance & Evidence