反应详情

Into the reaction apparatus used in Example 1, 160 g of ethyl alcohol, 18.3 g of lysine hydrochloride and 4.0 g of sodium hydroxide were charged. The resulting mixture was heated, refluxing the solvent, while being stirred, and was kept for 3 hours. The resultant product was cooled to room temperature and the by-product sodium chloride was filtered off therefrom. The solvent was distilled off from the obtained product to obtain 14.3 g of lysine in a syrup state. The lysine obtained, 15.8 g of allantoin and 150 ml of water were charged into the apparatus.

1. additionwere charged
2. temperatureThe resulting mixture was heated
3. temperaturerefluxing the solvent
4. filtrationthe by-product sodium chloride was filtered off
5. distillationThe solvent was distilled off from the obtained product