Formaldehyde → HCID 21421699, compound

HRID 259416Notes

Reaction equation

HRID 259416 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH:10]2[CH2:15][C:14]([CH3:17])([CH3:16])[NH:13][C:12]([CH3:19])([CH3:18])[CH2:11]2)[CH:5]=[C:6]([CH3:9])[C:7]=1[OH:8].[CH2:20]=O>C(O)=O>[CH3:1][C:2]1[CH:3]=[C:4]([CH:10]2[CH2:15][C:14]([CH3:17])([CH3:16])[N:13]([CH3:20])[C:12]([CH3:19])([CH3:18])[CH2:11]2)[CH:5]=[C:6]([CH3:9])[C:7]=1[OH:8]

Participants

4

Reactant 2

HCID 712FormaldehydeHCID 20494021HCID 20494021, compound

Product 1

HCID 21421699HCID 21421699, compound

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

3.0 Parts by weight of 4-(3',5'-dimethyl-4'-hydroxyphenyl)-2,2,6,6-tetramethylpiperidine was dissolved in formic acid and treated with 1.0 part by weight of formaldehyde on a steam bath. After heating for 12 hours the solution was cooled and basified in aqueous solution. The basification liquor was extracted into ether, the ethereal layer dried with magnesium sulphate and evaporated under reduced pressure. Crystallisation of the residue from petroleum (b.p. 80°-100°) have 1.9 parts by weight of product melting at 144°-6°.

Workup

  1. temperatureAfter heating for 12 hours the solution
  2. temperaturewas cooled
  3. extractionThe basification liquor was extracted into ether
  4. dry with materialthe ethereal layer dried with magnesium sulphate
  5. customevaporated under reduced pressure
  6. customCrystallisation of the residue from petroleum (b.p. 80°-100°)

Sources & evidence

ORD record
ord-c7cebbd935f041d194e725fe963bf810
Source dataset
uspto-grants-1977_07
Patent number
US04038280

Reaction notes

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