Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionyl Chloride → HCID 21421761, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | Desethyl-etomidate | HCID 297427 | — |
| 생성물 | HCID 21421761 | HCID 21421761 | 94% |
반응 단계
A mixture of 25.5 parts of (-)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic acid and 280 parts of sulfinyl chloride is stirred and refluxed for 2 hours. The reaction mixture is cooled in an ice-bath. The product crystallizes upon the addtion of 2,2'-oxybispropane. It is filtered off, washed with 2,2'-oxybispropane and dried, yielding 94% of (-)-1-(1-phenylethyl)-1H-imidazole-5-carbonyl chloride hydrochloride.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04038286 |
| 출처 데이터셋 | uspto-grants-1977_07 |
| ORD ID | ord-df2c3172bd7548a9a230ee5fd86621c1 |
| 출처 메모 | uspto-grants-1977_07 |