Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trimethyl orthoformate → 4-(2-Carboxyethenyl)benzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trimethyl orthoformate | HCID 9005 | — |
| 반응물 | 2-Propenoic acid, 3-(4-formylphenyl)- | HCID 98077 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 4-(2-Carboxyethenyl)benzoic acid | HCID 89196 | — |
반응 단계
A solution of 37.0 g of 4-formylcinnamic acid in 22 ml of trimethyl orthoformate and 600 ml of methanol was heated under reflux for 17 hrs. with stirring. At the end of this time, 100 ml of methanol was added and the reaction mixture was heated under reflux for an additional 5 hrs. and then allowed to cool to room temperature. The precipitate was collected, washed with methanol and dried at 75°-80° overnight to give 7.36 g of 4-carboxycinnamic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04038289 |
| 출처 데이터셋 | uspto-grants-1977_07 |
| ORD ID | ord-081276a15ba547f89388c4ebbb1a2408 |
| 출처 메모 | uspto-grants-1977_07 |