Bromine → HCID 178465859, compound

HRID 259520Notes

Reaction equation

HRID 259520 reaction equation
[C:1]([C:4]1[C:13]([CH3:14])=[N+:12]([O-:15])[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N+:5]=1[O-:16])(=[O:3])[CH3:2].[Br:17]Br>CO>[C:1]([C:4]1[C:13]([CH2:14][Br:17])=[N+:12]([O-:15])[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N+:5]=1[O-:16])(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 24408BromineHCID 178466988HCID 178466988, compound

Product 1

HCID 178465859HCID 178465859, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a stirred suspension of 2-acetyl-3-methylquinoxaline-1,4-dioxide (1.57 moles) in 3 liters of methanol was added bromine (1.74 moles) over a period of 2 hours. The reaction mixture was then stirred for 5 days at room temperature. The resulting yellow solid was collected by filtration, washed with methanol and ether. Yield, 331 grams (71%); m.p. 164-6° C.

Workup

  1. filtrationThe resulting yellow solid was collected by filtration
  2. washwashed with methanol and ether
  3. customYield

Sources & evidence

ORD record
ord-e5d1956381bb466d9c9d93ba3a0fd880
Source dataset
uspto-grants-1977_07
Patent number
US04038392

Reaction notes

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