反应详情

16 gm (0.08 mol) of 2-methyl-4,5-dimethoxy-benzene sulfonamide were dissolved in 500 ml of an aqueous 5% sodium hydroxide solution, and the solution was heated at its boiling point for 2 hours after addition of 39.6 gm (0.25 mol) of potassium permanganate. After cooling, the reaction mixture was suction-filtered through celite, and the desired product was precipitated by addition of concentrated hydrochloric acid. Rf -value (benzene/acetone = 3/1): 0.2-0.4.

1. temperaturethe solution was heated at its boiling point for 2 hours
2. temperatureAfter cooling
3. filtrationthe reaction mixture was suction-filtered through celite
4. customthe desired product was precipitated by addition of concentrated hydrochloric acid