HCID 20550077, compound → HCID 70620510, compound

HRID 259536Notes

Reaction equation

HRID 259536 reaction equation
[N+:1]([CH:4]=[C:5]([NH:16][CH2:17][CH2:18][S:19][CH2:20][C:21]1[S:22][CH:23]=[CH:24][N:25]=1)[NH:6][CH2:7][CH2:8][S:9][CH2:10][C:11]1[S:12][CH:13]=[CH:14][N:15]=1)([O-:3])=[O:2].I([O-])(=O)(=O)=[O:27].[Na+]>O>[N+:1]([CH:4]=[C:5]([NH:16][CH2:17][CH2:18][S:19][CH2:20][C:21]1[S:22][CH:23]=[CH:24][N:25]=1)[NH:6][CH2:7][CH2:8][S:9]([CH2:10][C:11]1[S:12][CH:13]=[CH:14][N:15]=1)=[O:27])([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 20550077HCID 20550077, compoundHCID 23667635Sodium periodate

Product 1

HCID 70620510HCID 70620510, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

1-Nitro-2,2-bis-[2-(2-thiazolylmethylthio)ethylamino]ethylene (4.5 g) was added to a stirred solution of an equivalent amount of sodium metaperiodate (2.3 g) in water (1600 ml), and the resulting solution was stirred at room temperature for 20 hours. Evaporation of the solvent and chromatographic purification of the residue on silica gel gave the title product as an oil. The structure of the product was confirmed by the 100 mHz n.m.r. spectrum in 2H6 -dimethylsulphoxide which showed the following resonances:

Workup

  1. customEvaporation of the solvent and chromatographic purification of the residue on silica gel

Sources & evidence

ORD record
ord-9a55d5a1cad14b21ad7cb22219877867
Source dataset
uspto-grants-1977_07
Patent number
US04038408

Reaction notes

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