3-Methoxy-2-(2-aminoethylsulphinylmethyl)pyridine → 1-Methylthio-2-nitro-1-[2-((3-methoxy-2-pyridyl)methylsulphinyl)ethylamino]ethylene

HRID 259537Notes

Reaction equation

HRID 259537 reaction equation
[CH3:1][O:2][C:3]1[C:4]([CH2:9][S:10]([CH2:12][CH2:13][NH2:14])=[O:11])=[N:5][CH:6]=[CH:7][CH:8]=1.[CH3:15][S:16][C:17](S(C)=O)=[CH:18][N+:19]([O-:21])=[O:20]>>[CH3:15][S:16][C:17]([NH:14][CH2:13][CH2:12][S:10]([CH2:9][C:4]1[C:3]([O:2][CH3:1])=[CH:8][CH:7]=[CH:6][N:5]=1)=[O:11])=[CH:18][N+:19]([O-:21])=[O:20]

Participants

3

Reactant 2

HCID 203154773-Methoxy-2-(2-aminoethylsulphinylmethyl)pyridineHCID 544870941-Nitro2-methylthio-2-methylsulphinylethylene

Product 1

HCID 706204771-Methylthio-2-nitro-1-[2-((3-methoxy-2-pyridyl)methylsulphinyl)ethylamino]ethylene

Procedure

Reaction of 3-methoxy-2-(2-aminoethylsulphinylmethyl)-pyridine with 1-methylthio-1-methylsulphinyl-2-nitroethylene yields 1-methylthio-2-nitro-1-[2-((3-methoxy-2-pyridyl)methylsulphinyl)ethylamino]ethylene which, when reacted with 4-(4-aminobutyl)imidazole yields 1-nitro-2-[2-((3-methoxy-2-pyridyl)methylsulphinyl)ethylamino]-2-[4-(4-imidazolyl)butylamino]ethylene.

Sources & evidence

ORD record
ord-4b8b80484150468499ea4bf9d4b7d7bc
Source dataset
uspto-grants-1977_07
Patent number
US04038408

Reaction notes

Loading…