6-Methyl-2-nitropyridin-3-ol → 2-Amino-6-methylpyridin-3-ol

Participants

Reaction Steps

3-Hydroxy-6-methyl-2-nitropyridine (3.5 g.) in 75 ml. of methanol was reduced over 1 g. of 5% palladium-on-carbon catalyst. The catalyst was removed by filtration and the filtrate was concentrated to dryness to give 2-amino-3-hydroxy-6-methylpyridine which was used directly in the next stop.

Provenance & Evidence