反应详情

A solution of 0.63 g. of 2-(3-aminophenyl)oxazolo[4,5-b]pyridine in 10 ml. of pyridine was treated with 0.35 ml. of acetic anhydride with stirring. After stirring over the weekend the mixture was diluted to 50 ml. with water. After stirring a short time and cooling, the precipitate was collected, washed with water and dried. Recrystallization from ethyl acetate gave 2-(3-acetamidophenyl)oxazolo[4,5-b]pyridine, m.p. 201.5°-202.5°.

1. additionwas diluted to 50 ml
2. stirringAfter stirring a short time
3. temperaturecooling
4. customthe precipitate was collected
5. washwashed with water
6. customdried
7. customRecrystallization from ethyl acetate