反应详情

A solution of 100 mg. of 3-amino-5-nitro-2-pyridone in 1.5 ml. of pyridine was cooled and treated with 200 mg. of benzoyl chloride. After 2 hours water was added. The oil that separated was washed with water and triturated with ether. The resultant solid was recrystallized from ethyl acetate to give 3-benzoylamino-5-nitro-2-pyridone, m.p. 267°-268° C.

1. additiontreated with 200 mg
2. customThe oil that separated
3. washwas washed with water
4. customtriturated with ether
5. customThe resultant solid was recrystallized from ethyl acetate