Pyridine → 5-Isopropoxycarbonylamino-2-phenyloxazolo[5,4-b]pyridine

Participants

Reaction Steps

A mixture of 300 mg. of 5-amino-2-phenyloxazolo[ 5,4-b]pyridine and 3 ml. of pyridine was cooled in ice and to it was added 0.2 ml. of isopropylchloroformate. The mixture was allowed to age in the refrigerator for 5 days, and diluted with ice and water. The precipitate was collected and recrystallized from isopropanol to give 5-isopropoxycarbonylamino-2-phenyloxazolo[ 5,4-b]pyridine, m.p. 210°-211° C.

Provenance & Evidence