2-[3,5-Di(2-methylallyl)phenyl]oxazolo[4,5-b]pyridine → 2-[3,5-Bis(2-methylpropyl)phenyl][1,3]oxazolo[4,5-b]pyridine

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Reaction Steps

The product from Step B (3 mmoles) is hydrogenated in 25 ml. of methanol in the presence of 500 mg. of 5% palladium on carbon under 3 atmospheres of hydrogen. The catalyst is removed by filtration and the filtrate is concentrated to dryness. The residue is recrystallized from n-hexane to give 2-[3,5-di(isobutyl)phenyl]oxazolo[4,5-b]pyridine.

Provenance & Evidence