Sodium methanethiolate → HCID 22916502, compound

HRID 259699Notes

Reaction equation

HRID 259699 reaction equation
[CH3:1][S-:2].[Na+].[N+:4]([C:7]1[C:12]([Cl:13])=[CH:11][CH:10]=[CH:9][C:8]=1[C:14](=[O:17])[CH2:15]Br)([O-:6])=[O:5]>CO>[N+:4]([C:7]1[C:12]([Cl:13])=[CH:11][CH:10]=[CH:9][C:8]=1[C:14](=[O:17])[CH2:15][S:2][CH3:1])([O-:6])=[O:5]

Participants

4

Reactant 2

HCID 4378561Sodium methanethiolateHCID 22916503HCID 22916503, compound

Product 1

HCID 22916502HCID 22916502, compoundYield 36.3%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1.5 g (0.0061 mol) of 2'-nitro-3'-chloro-2-(methylthio)acetophenone are prepared by addition at 0° C. of 1.3 g (0.018 mol) of sodium methanethiolate in solution in 10 ml of methanol to 4.7 g (0.0168 mol) of 2'-nitro-3'-chloro-2-bromoacetophenone obtained above.

Workup

  1. customobtained above

Sources & evidence

ORD record
ord-498d7285c5a9419a9ea77a342162ad66
Source dataset
uspto-grants-1996_06
Patent number
US05523280

Reaction notes

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