2-Benzoyl-4,5-dichlorobenzoic acid → HCID 21463235, compound

HRID 259749Notes

Reaction equation

HRID 259749 reaction equation
[C:1]([C:9]1[CH:17]=[C:16]([Cl:18])[C:15]([Cl:19])=[CH:14][C:10]=1[C:11]([OH:13])=[O:12])(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(C1C=C(C)C(C)=C[C:29]=1[C:30]([OH:32])=[O:31])(=O)C1C=CC=CC=1>>[Cl:18][C:16]1[CH:17]=[C:9]2[C:10](=[CH:14][C:15]=1[Cl:19])[C:11](=[O:12])[O:13][C:29]([C:30]([OH:32])=[O:31])=[C:1]2[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 122052912-Benzoyl-4,5-dichlorobenzoic acidHCID 15214193HCID 15214193, compound

Product 1

HCID 21463235HCID 21463235, compound

Procedure

Using 2-benzoyl-4,5-dichlorobenzoic acid in lieu of 2-benzoyl-4,5-dimethylbenzoic acid, the procedure of Step 1 of Reference Example 1 was otherwise repeated to provide 6,7-dichloro-4-phenylisocoumarin-3-carboxylic acid [m.p. 243°-244° C. (recrystallized from ethyl acetate-isopropyl ether)]. This compound was reacted and treated in the same manner as in Step 2 of Reference Example 1 to provide the title compound as colorless crystals.

Sources & evidence

ORD record
ord-a9a6ec1b98c04ac08e7197b6e518b3cc
Source dataset
uspto-grants-1996_06
Patent number
US05523305

Reaction notes

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