1H-Pyrrole, 2-(3,5-dibromo-2-methoxyphenyl)- → HCID 22403107, compound
Reaction equation
[Cl:1][C:2]1[CH:11]=[C:10]([C:12]2[NH:13][CH:14]=[CH:15][CH:16]=2)[CH:5]2[O:6][CH:7]=[CH:8][CH:9]=[C:4]2[CH:3]=1.BrC1C(OC)=[C:20]([C:25]2[NH:26][CH:27]=CC=2)[CH:21]=[C:22](Br)[CH:23]=1>>[ClH:1].[Cl:1][C:2]1[CH:11]=[C:10]([C:12]2[NH:13][C:14]([CH2:27][N:26]3[CH2:25][CH2:20][CH2:21][CH2:22][CH2:23]3)=[CH:15][CH:16]=2)[CH:5]2[O:6][CH:7]=[CH:8][CH:9]=[C:4]2[CH:3]=1Participants
3
Procedure
This compound was prepared by a method analogous to that used to prepare example 1, but using 2-(6-chloro-benzo[b]pyran-8-yl)-1H-pyrrole (prepared according to the method of Kruse et at., [Heterocycles, 26,3141, 1987] from the corresponding acid chloride) in place of 2-(3,5-dibromo-2-methoxyphenyl)-1H-pyrrole.
Workup
- customThis compound was prepared by a method analogous to
- customto prepare example 1
- customprepared
Sources & evidence
- ORD record
- ord-1779edeca9a24547b49d61b67c9e9917
- Source dataset
- uspto-grants-1996_06
- Patent number
- US05523299
Reaction notes
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