2-[5-(Ethanesulfonyl)-2-methoxyphenyl]-1H-pyrrole → HCID 22403071, compound

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Reaction Steps

This compound was prepared by a method analogous to that used to prepare example 2, but using 2-(3-bromo-5ethylsulphonyl-2-methoxy-phenyl)-1H-pyrrole (prepared according to the method of Kruse et al., [Heterocycles, 26,3141, 1987] from the corresponding acid chloride) in place of 2-(5-ethylsulphonyl-2-methoxyphenyl)-1H-pyrrole. NMR δ(CDCl3) 1.30-1.70 (9H, m), 2.40 (4H, m), 3.15 (2H, q, J=7 Hz), 3.50 (2H, s), 3.80 (3H, s), 6.10 (1H, t, J=2 Hz), 6.60 (1H, t, J=2 Hz), 7.80 (1H, d, J=1 Hz), 8.00 (1H, d, J=1 Hz), 9.9 (1H, s).

Provenance & Evidence