HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methoxyphenylacetaldehyde → 1-Benzhydrylamino-2-(4-methoxyphenyl)-ethanephosphonous acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methoxyphenylacetaldehyde | HCID 79782 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | HCID 178527021 | HCID 178527021 | — |
| Product | 1-Benzhydrylamino-2-(4-methoxyphenyl)-ethanephosphonous acid | HCID 21325881 | — |
Reaction Steps
10 parts of freshly distilled p-methoxyphenylacetaldehyde in 20 parts of sodium-dried dioxan was added to a suspension of 17 parts of benzhydrylammonium hypophosphite in 100 parts of sodium-dried dioxan under reflux and under nitrogen as in Example 17 above. 70 Parts dioxan/water was removed. 125 Parts of alcohol was added and DL-1-benzhydrylamino-2-(4-methoxyphenyl)-ethanephosphonous acid, melting point 199°-202°, was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04147780 |
| Source dataset | uspto-grants-1979_04 |
| ORD ID | ord-dd34e67a365840f7bd89be9836dcf4be |
| Source note | uspto-grants-1979_04 |