HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 2-Amino-5-fluorobenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 2-Bromo-5-fluorobenzoic acid | HCID 2778181 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | Potassium | HCID 5462222 | — |
| Solvent | Potassium Hydroxide | HCID 14797 | — |
| Product | 2-Amino-5-fluorobenzoic acid | HCID 101412 | — |
Reaction Steps
If the sodium salt solution of 5-fluoro-2-bromobenzoic acid is replaced by aliquot parts of the potassium or ammonium salt solution, prepared by dissolving 219 parts of 5-fluoro-2-bromobenzoic acid in 256.1 parts of 21.9% strength aqueous potassium hydroxide or, respectively, 217 parts of 7.9% aqueous ammonia solution and used as the metering medium in a procedure otherwise identical to that indicated, then 5-fluoroanthranilic acid is obtained in identical yield and quality.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05523472 |
| Source dataset | uspto-grants-1996_06 |
| ORD ID | ord-4f2f20decea5457bb0487fd375f40d1a |
| Source note | uspto-grants-1996_06 |