1-Benzhydrylamino-2-(indol-3-yl)-ethanephosphonous acid → 1-Amino-2-(indol-3-yl)-ethanephosphonous acid

HRID 25996Notes

Reaction equation

HRID 25996 reaction equation
C([NH:14][CH:15]([P:26]([OH:28])[OH:27])[CH2:16][C:17]1[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[NH:19][CH:18]=1)(C1C=CC=CC=1)C1C=CC=CC=1.C(NC(P(O)O)C(C)C)(C1C=CC=CC=1)C1C=CC=CC=1>>[NH2:14][CH:15]([P:26]([OH:28])[OH:27])[CH2:16][C:17]1[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[NH:19][CH:18]=1

Participants

3

Reactant 2

HCID 213258571-Benzhydrylamino-2-(indol-3-yl)-ethanephosphonous acidHCID 213258821-Benzhydrylamino-2-methylpropanephosphonous acid

Product 1

HCID 213258651-Amino-2-(indol-3-yl)-ethanephosphonous acid

Procedure

The procedure described in Example 36B was repeated using DL-1-benzhydrylamino-2-(indol-3-yl)-ethanephosphonous acid instead of DL-1-benzhydrylamino-2-methylpropanephosphonous acid to give DL-1-amino-2-(indol-3-yl)-ethanephosphonous acid.

Sources & evidence

ORD record
ord-c2931da47b30492890e7be1818744cc2
Source dataset
uspto-grants-1979_04
Patent number
US04147780

Reaction notes

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