反应详情

45.23 Grams of 2,3-dichloro-1-propene were added dropwise to a mixture of 20.00 g of cyclohexanone, 60 g of toluene, 60 g of water and 26.65 g of zinc powder at 35° C., and after the addition, the resultant mixture was maintained at the same temperature for 5 hours. After the reaction was completed, zinc-derived insolubles were filtered off, and the resultant filtrate was separated. The organic phase thereof was washed with a 7% sodium carbonate aqueous solution, and dried over magnesium sulfate. The desiccant was filtered off, and the resultant toluene solution was concentrated under reduced pressure to give 32.75 g of 1-(2'-chloroallyl)-1-cyclohexanol; nD20 =1.495, EI-MS m/e 156 (M-H2O+), 158 (M-H2O+2+).

1. additionafter the addition
2. filtrationwere filtered off
3. customthe resultant filtrate was separated
4. washThe organic phase thereof was washed with a 7% sodium carbonate aqueous solution
5. dry with materialdried over magnesium sulfate
6. filtrationThe desiccant was filtered off
7. concentrationthe resultant toluene solution was concentrated under reduced pressure