HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide → 6-Amino-5-(adamantan-1-yl)acetylamino-1,3-dipropyluracil
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide | HCID 15908 | — |
| Reactant | 1-Adamantaneacetic acid | HCID 123221 | — |
| Reactant | 5,6-Diamino-1,3-dipropyl-2,4(1H,3H)-pyrimidinedione | HCID 5098605 | — |
| Product | 6-Amino-5-(adamantan-1-yl)acetylamino-1,3-dipropyluracil | HCID 15750284 | 112.8% |
Reaction Steps
At first 2.00 g (8.85 mmol) of 1,3-dipropyl-5,6-diaminouracil and 2.06 g (10.6 mmol) of 1-adamantaneacetic acid were condensed according to the procedure of Example 1 using 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide to afford 4.02 g (yield: 100%) of amorphous 6-amino-5-(adamantan-1-yl)acetylamino-1,3-dipropyluracil as a crude product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05525607 |
| Source dataset | uspto-grants-1996_06 |
| ORD ID | ord-acc5d3f03b6c47999ac263f677135dbe |
| Source note | uspto-grants-1996_06 |