HCID 22402291, compound → HCID 22402287, compound

HRID 260042Notes

Reaction equation

HRID 260042 reaction equation
[N:1]1([C:8](=[O:32])[CH:9]([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[CH2:10][CH2:11][N:12]2[CH2:17][CH2:16][C:15](O)([C:18]3[S:19][CH:20]=[CH:21][C:22]=3[O:23][CH3:24])[CH2:14][CH2:13]2)[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1>C(O)(=O)C>[N:1]1([C:8](=[O:32])[CH:9]([C:26]2[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=2)[CH2:10][CH2:11][N:12]2[CH2:13][CH:14]=[C:15]([C:18]3[S:19][CH:20]=[CH:21][C:22]=3[O:23][CH3:24])[CH2:16][CH2:17]2)[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 1

HCID 22402291HCID 22402291, compound

Product 1

HCID 22402287HCID 22402287, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

The title compound was prepared from 1-azepan-1-yl-4-[4-hydroxy-4-(3-methoxy-thiophen-2-yl)-piperidin-1-yl]-2-phenyl-butan-1-one (1.35 g, 2.9 mmole) and acetic acid (80 mL) in the manner previously described above to yield 1.1 g of product, m.p. 108°-12 ° C.

Sources & evidence

ORD record
ord-388a23026659419eaecebb65badccc37
Source dataset
uspto-grants-1996_06
Patent number
US05525600

Reaction notes

Loading…