HRID260079

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID143742

4-Methoxy-3-methylbenzyl chloride

C9H11ClO

结构：CCOC(=O)C1Cc2c(ccc(OC)c2O)CN1C(=O)C(c1ccccc1)c1ccccc1

HCID15296729

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)C1Cc2c(ccc(OC)c2OCc2ccc(OC)c(C)c2)CN1C(=O)C(c1ccccc1)c1ccccc1

HCID15230314

未命名化合物

PROCEDURE

实验过程

This compound is prepared from the phenol derivative of Example 31 and 4-methoxy-3-methyl benzyl chloride by a procedure similar to that in Example 32. The product is purified by silica gel chromatography; tlc (1:1 ethyl-acetate/hexane), one spot, Rf 0.7.

WORKUP

后处理

customThe product is purified by silica gel chromatography

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-4bdc901a3e9541aa894e748e1b4136c5
来源数据集: uspto-grants-1996_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05525614
来源说明: uspto-grants-1996_06

反应 SMILES

[C:1]1([CH:7]([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[C:8]([N:10]2[CH:19]([C:20]([O:22][CH2:23][CH3:24])=[O:21])[CH2:18][C:17]3[C:12](=[CH:13][CH:14]=[C:15]([O:26][CH3:27])[C:16]=3[OH:25])[CH2:11]2)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:34][O:35][C:36]1[CH:43]=[CH:42][C:39]([CH2:40]Cl)=[CH:38][C:37]=1[CH3:44]>>[C:28]1([CH:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[C:8]([N:10]2[CH:19]([C:20]([O:22][CH2:23][CH3:24])=[O:21])[CH2:18][C:17]3[C:12](=[CH:13][CH:14]=[C:15]([O:26][CH3:27])[C:16]=3[O:25][CH2:40][C:39]3[CH:42]=[CH:43][C:36]([O:35][CH3:34])=[C:37]([CH3:44])[CH:38]=3)[CH2:11]2)=[O:9])[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=1