HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-(4-Chlorobenzoyl)-2-methyl-benzenehexanoic acid chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-(4-Chlorobenzoyl)-2-methylbenzene hexanoic acid | HCID 20534489 | — |
| Product | 3-(4-Chlorobenzoyl)-2-methyl-benzenehexanoic acid chloride | HCID 54148246 | — |
Reaction Steps
Using the procedure of Example 2, 3-(4-chlorobenzoyl)-2-methylbenzene hexanoic acid was reacted with thionyl chloride to form 3-(4-chlorobenzoyl)-2-methyl-benzenehexanoic acid chloride which was then reacted with 4-(3-trifluoromethylphenyl)-1-piperazinyl-ethanol followed by hydrochloric acid to obtain 2-[4-(3-trifluoromethylphenyl)-1-piperazinyl]-ethyl 3-(4-chlorobenzoyl)-2-methyl-benzenehexanoate hydrochloride melting at 108° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04147790 |
| Source dataset | uspto-grants-1979_04 |
| ORD ID | ord-0fd6484f08c942b2824a17c081cb68e6 |
| Source note | uspto-grants-1979_04 |