Butoxy(oxo)acetate → Butyl 2-oxo-2-((3-(2H-tetrazol-5-yl)phenyl)amino)acetate

Participants

Reaction Steps

5-(3-Aminophenyl)tetrazole (1.7 g) was added to 12 ml of n-butyloxalate and reacted at a bath temperature of 165° to 175° C. for 1.5 hr while stirring. After cooling, the precipitated crystals were filtered off and recrystallized from acetone-n-hexane, to give 2.3 g (yield: 75%) of 5-(3-n-butyloxalylaminophenyl)tetrazole.

Provenance & Evidence