反应详情

Boc-Gly-Gly-Ala-Pro-OBzl (30.0 g, 0.061 mole) was dissolved in glacial acetic acid (300 mL) and 3.0 g of 10% Palladium on activated charcoal was added. This mixture was hydrogenated at 40 psi for 6 h. The reaction mixture was filtered through celite and the solvent was removed in vacuum. The resulting residue was triturated with ether, faltered, washed with ether, and dried to obtain Boc-Gly-Gly-Ala-Pro-OH.

1. filtrationThe reaction mixture was filtered through celite
2. customthe solvent was removed in vacuum
3. customThe resulting residue was triturated with ether
4. washwashed with ether
5. customdried