Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pyridine → 2-Pyrrolidinone, 3-hydroxy-1-methyl-5-(3-pyridinyl)-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | 3'-Hydroxycotinine, trans- | HCID 107963 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 용매 | Succinic anhydride | HCID 7922 | — |
| 생성물 | 2-Pyrrolidinone, 3-hydroxy-1-methyl-5-(3-pyridinyl)- | HCID 414 | — |
반응 단계
Hydroxycotinine hemisuccinate was prepared as follows. In a glass tube, 19 mg of trans-3'-hydroxycotinine were dissolved in 1 ml of DMF. In this solution 21 mg of succinic anhydride were dissolved. After adding 20 μl of pyridine, the tube was covered (PARAFILM®) and incubated overnight at 37° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05527686 |
| 출처 데이터셋 | uspto-grants-1996_06 |
| ORD ID | ord-75f5640dafa64d76af267b510fdfec74 |
| 출처 메모 | uspto-grants-1996_06 |