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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 260286Generated: October 26, 2026

Phenol → 1-Naphthyloxy proline amide

https://huagongshe.com/reaction/260286

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenolHCID 996—
Reactant1-NaphtholHCID 7005—
Reactantn-t-Butyl-4(s)-phenoxy-l-prolineamide trifluoroacetic acid saltHCID 22862000—
Product1-Naphthyloxy proline amideHCID 22861992—

Reaction Steps

Following substantially the same procedure for synthesizing N-t-butyl-4(S)-phenoxy-L-prolineamide trifluoroacetic acid salt as outlined in Example 1, Steps 6 through 8, but substituting 1-naphthol for the phenol used therein, the 1-naphthyloxy proline amide was produced.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05527799
Source datasetuspto-grants-1996_06
ORD IDord-1bdfafd9470c41ff803e450f62e2f2bc
Source noteuspto-grants-1996_06