HCID 54083298, compound → HCID 53761179, compound

HRID 260304Notes

Reaction equation

HRID 260304 reaction equation
[CH3:1][CH:2]1[CH:26]=[C:25]2[C@:20]([CH3:28])([CH2:21][CH2:22][C:23](=[O:27])[NH:24]2)[C@@H:19]2[C@@H:3]1[C@H:4]1[C@:16]([CH3:29])([CH2:17][CH2:18]2)[C@@H:7]([C@H:8]([CH3:15])[CH2:9][CH2:10][CH2:11][CH:12]([CH3:14])[CH3:13])[CH2:6][CH2:5]1>CC(O)=O>[CH3:1][CH:2]1[CH2:26][CH:25]2[C@:20]([CH3:28])([CH2:21][CH2:22][C:23](=[O:27])[NH:24]2)[C@@H:19]2[C@@H:3]1[C@H:4]1[C@:16]([CH3:29])([CH2:17][CH2:18]2)[C@@H:7]([C@H:8]([CH3:15])[CH2:9][CH2:10][CH2:11][CH:12]([CH3:13])[CH3:14])[CH2:6][CH2:5]1

Participants

3

Reactant 1

HCID 54083298HCID 54083298, compound

Product 1

HCID 53761179HCID 53761179, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Following the analogous general procedure of Example 8, compound 29 was catalytically hydrogenated in HOAc to yield the title compound 30.

Sources & evidence

ORD record
ord-4cc0dbd571f043d7ae61b13835e0f4ed
Source dataset
uspto-grants-1996_06
Patent number
US05527807

Reaction notes

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