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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 260308Generated: October 31, 2026

(2S,4S)-4-Acetylthio-1-allyloxycarbonyl-2-carboxypyrrolidine → (2S,4S)-4-acetylthio-1-allyloxycarbonyl-2-(6-allyloxy-3-(E-2-allyloxycarbonyl-1-ethenyl)phenylcarbamoyl)pyrrolidine

https://huagongshe.com/reaction/260308

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S,4S)-4-Acetylthio-1-allyloxycarbonyl-2-carboxypyrrolidineHCID 15299255—
ReactantAllyl 4-allyloxy-3-aminocinnamateHCID 54090444—
ReactantAllyl 3-aminocinnamateHCID 54165426—
Product(2S,4S)-4-acetylthio-1-allyloxycarbonyl-2-(6-allyloxy-3-(E-2-allyloxycarbonyl-1-ethenyl)phenylcarbamoyl)pyrrolidineHCID 86749573—

Reaction Steps

Allyl 4-allyloxy-3-aminocinnamate was condensed with (2S,4S)-4-acetylthio-1-allyloxycarbonyl-2-carboxypyrrolidine by the method described in example 1 for allyl 3-aminocinnamate to give (2S,4S)-4-acetylthio-1-allyloxycarbonyl-2-(6-allyloxy-3-(E-2-allyloxycarbonyl-1-ethenyl)phenylcarbamoyl)pyrrolidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05527791
Source datasetuspto-grants-1996_06
ORD IDord-1eea76a397184006aa501dbfecfceb1a
Source noteuspto-grants-1996_06