HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Methyl 2-aminohex-5-enoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | 5-Hexenoic acid, 2-[(phenylmethylene)amino]-, methyl ester | HCID 12039461 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | Methyl 2-aminohex-5-enoate | HCID 15356347 | — |
Reaction Steps
Dissolve N-(phenylmethylene)-2-(3-butenyl)glycine methyl ester (25 g) in ethyl ether (400 mL) and stir with 1N hydrochloric acid (150 mL) and water (150 mL). Place under an argon atmosphere and stir for 2 hours. Separate the aqueous phase and adjust to pH 9, extract into chloroform, dry and evaporate the solvent in vacuo to give the title compound as a light oil (4.5 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05527795 |
| Source dataset | uspto-grants-1996_06 |
| ORD ID | ord-e23eca4430514afd863a554eb8cca2b7 |
| Source note | uspto-grants-1996_06 |