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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 260489Generated: October 27, 2026

3-Methylhistamine → N-[2-(3-methylimidazol-4-yl)ethyl]-3-phenylsulfonyl-5-chloroindole-2-carboxamide

https://huagongshe.com/reaction/260489

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-MethylhistamineHCID 69520—
Reactant3-Phenylsulfonyl-5-chloroindole-2-carboxylic acidHCID 15813516—
ProductN-[2-(3-methylimidazol-4-yl)ethyl]-3-phenylsulfonyl-5-chloroindole-2-carboxamideHCID 22401494—

Reaction Steps

Reaction of 3-phenylsulfonyl-5-chloroindole-2-carboxylic acid with 3-methylhistamine under the conditions of Example 37 gave the title compound, mp 257°-258.5° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05527819
Source datasetuspto-grants-1996_06
ORD IDord-a52c92936c9046218a013afa76db3325
Source noteuspto-grants-1996_06