Boron tribromide → HCID 483556, compound

HRID 260492Notes

Reaction equation

HRID 260492 reaction equation
C[O:2][C:3]1[CH:8]=[C:7]([CH2:9][NH:10][C:11]([C:13]2[NH:14][C:15]3[C:20]([C:21]=2[S:22]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)(=[O:24])=[O:23])=[CH:19][C:18]([Cl:31])=[CH:17][CH:16]=3)=[O:12])[CH:6]=[CH:5][N:4]=1.B(Br)(Br)Br>C(Cl)Cl>[Cl:31][C:18]1[CH:19]=[C:20]2[C:15](=[CH:16][CH:17]=1)[NH:14][C:13]([C:11]([NH:10][CH2:9][C:7]1[CH:6]=[CH:5][NH:4][C:3](=[O:2])[CH:8]=1)=[O:12])=[C:21]2[S:22]([C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)(=[O:24])=[O:23]

Participants

4

Reactant 2

HCID 25134Boron tribromideHCID 22401480HCID 22401480, compound

Product 1

HCID 483556HCID 483556, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Reaction of N-(2-methoxy-4-pyridylmethyl)-5-chloro-3-phenylsulfonylindole-2-carboxamide with boron tribromide in methylene chloride at 0° C. to room temperature, according to the procedure described in Example 39, provides the title compound.

Sources & evidence

ORD record
ord-0dcbba6507784e6389b77eeeef2cd6c1
Source dataset
uspto-grants-1996_06
Patent number
US05527819

Reaction notes

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