5-Ethyl-3-methoxy-4-methoxymethoxy-1-naphthalenecarbaldehyde → 5'-Ethyl-3'-methoxy-4'-methoxymethoxy-1'-valeronaphthone

HRID 260577Notes

Reaction equation

HRID 260577 reaction equation
[CH2:1]([C:3]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:4]=1[C:5]([O:17][CH2:18][O:19][CH3:20])=[C:6]([O:15][CH3:16])[CH:7]=[C:8]2[CH:13]=[O:14])[CH3:2].[CH2:21]([Li])[CH2:22][CH2:23][CH3:24]>CCCCCC>[CH2:1]([C:3]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:4]=1[C:5]([O:17][CH2:18][O:19][CH3:20])=[C:6]([O:15][CH3:16])[CH:7]=[C:8]2[C:13](=[O:14])[CH2:21][CH2:22][CH2:23][CH3:24])[CH3:2]

Participants

4

Reactant 2

HCID 99705695-Ethyl-3-methoxy-4-methoxymethoxy-1-naphthalenecarbaldehydeHCID 178418339Butyllithium

Product 1

HCID 117241945'-Ethyl-3'-methoxy-4'-methoxymethoxy-1'-valeronaphthone

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

5-Ethyl-3-methoxy-4-methoxymethoxy-1-naphthalenecarbaldehyde and a hexane solution of 1.6M n-butyl lithium were used and treated in the same manner as in Reference 6 to obtain the captioned compound as a yellow oily substance.

Workup

  1. additiontreated in the same manner as in Reference 6
  2. customto obtain the captioned compound as a yellow oily substance

Sources & evidence

ORD record
ord-d0780072ab4646fbb001971470793c10
Source dataset
uspto-grants-1996_06
Patent number
US05527948

Reaction notes

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