反应详情

100 g (0.55 mol) of 8-aminonaphth-2-ol are poured into 125 ml (135.25 g or 1.325 mol) of acetic anhydride cooled in an ice bath, and the mixture is stirred under cold conditions for 1 h. The mixture obtained is poured into 375 ml of ice-water and stirred for several hours. The violet solid is collected by filtration, washed three times with 30 ml of diethyl ether and dried under reduced pressure. 108.8 g of a product melting point: 193°-195° C. are obtained which is used as it is in the following step.

1. temperaturecooled in an ice bath
2. customThe mixture obtained
3. stirringstirred for several hours
4. filtrationThe violet solid is collected by filtration
5. washwashed three times with 30 ml of diethyl ether
6. customdried under reduced pressure