Ethyl 4-[3-[8-(4-isobutylphenyl)undecanoyl]1-indolyl]butyrate → HCID 22400459, compound

HRID 260852Notes

Reaction equation

HRID 260852 reaction equation
[CH2:1]([C:5]1[CH:10]=[CH:9][C:8]([CH:11]([O:16][CH2:17][CH2:18][CH2:19][CH2:20][C:21]([C:23]2[C:31]3[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=3)[N:25]([CH2:32][CH2:33][CH2:34][C:35]([O:37]CC)=[O:36])[CH:24]=2)=[O:22])[CH2:12][CH2:13][CH2:14][CH3:15])=[CH:7][CH:6]=1)[CH:2]([CH3:4])[CH3:3].C(C1C=CC(C(CCC)CCCCCCC(C2C3C(=CC=CC=3)N(CCCC(OCC)=O)C=2)=O)=CC=1)C(C)C>>[CH2:1]([C:5]1[CH:6]=[CH:7][C:8]([CH:11]([O:16][CH2:17][CH2:18][CH2:19][CH2:20][C:21]([C:23]2[C:31]3[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=3)[N:25]([CH2:32][CH2:33][CH2:34][C:35]([OH:37])=[O:36])[CH:24]=2)=[O:22])[CH2:12][CH2:13][CH2:14][CH3:15])=[CH:9][CH:10]=1)[CH:2]([CH3:4])[CH3:3]

Participants

3

Reactant 2

HCID 22400460Ethyl 4-[3-[8-(4-isobutylphenyl)undecanoyl]1-indolyl]butyrateHCID 22400484HCID 22400484, compound

Product 1

HCID 22400459HCID 22400459, compound

Procedure

The procedure of Ex. 16 was repeated except that ethyl 4-[3-[5-[1-(4-isobutylphenyl)pentyloxy]valeryl]-1-indolyl]butyrate obtained in Ex. 36 was used in place of ethyl 4-[3-[8-(4isobutylphenyl) undecanoyl]-1-indolyl]butyrate to give 4-[3-[5-[1-(4-isobutylphenyl)pentyloxy]valeryl]-1-indolyl]butyric acid.

Workup

  1. customobtained in Ex

Sources & evidence

ORD record
ord-831b532cb73343feb4d088e24413eab6
Source dataset
uspto-grants-1996_06
Patent number
US05530019

Reaction notes

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