(E)-4-methoxybenzyl 4-[3-(2-nonenoyl)-1-indolyl]butyrate → (E)-4-[3-(2-decenoyl)-1-indolyl]butyric acid

HRID 260857Notes

Reaction equation

HRID 260857 reaction equation
[C:1]([C:12]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[N:14]([CH2:21][CH2:22][CH2:23][C:24]([O:26]CC2C=CC(OC)=CC=2)=[O:25])[CH:13]=1)(=[O:11])/[CH:2]=[CH:3]/[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].C(C1C2C(=CC=CC=2)N(CCCC(OCC2C=CC(OC)=CC=2)=O)C=1)(=O)/C=C/CCCCCC>>[C:1]([C:12]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[N:14]([CH2:21][CH2:22][CH2:23][C:24]([OH:26])=[O:25])[CH:13]=1)(=[O:11])/[CH:2]=[CH:3]/[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

Participants

3

Reactant 2

HCID 22400455(E)-4-methoxybenzyl 4-[3-(2-nonenoyl)-1-indolyl]butyrateHCID 22400524(E)-4-methoxybenzyl 4-[3-(2-decenoyl)-1-indolyl]butyrate

Product 1

HCID 22400478(E)-4-[3-(2-decenoyl)-1-indolyl]butyric acid

Procedure

The procedure of Ex. 45 was repeated except that (E)-4-methoxybenzyl 4-[3-(2-decenoyl)-1-indolyl]butyrate obtained in Ex. 46 was used in place of (E)-4-methoxybenzyl 4-[3-(2-none-noyl)-1-indolyl]butyrate to give (E)-4-[3-(2-decenoyl)-1-indolyl]butyric acid.

Workup

  1. customobtained in Ex

Sources & evidence

ORD record
ord-e6864107a3d643cf907f96814f3821b2
Source dataset
uspto-grants-1996_06
Patent number
US05530019

Reaction notes

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