HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl 4-(3-nonyloxycarbonyl-1-indolyl)butyrate → 4-(3-Nonyloxycarbonyl-1-indolyl)butyric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl 4-(3-nonyloxycarbonyl-1-indolyl)butyrate | HCID 22400555 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 4-(3-Nonyloxycarbonyl-1-indolyl)butyric acid | HCID 22400533 | 82,978.297% |
Reaction Steps
A mixture of benzyl 4-(3-nonyloxycarbonyl-1-indolyl)butyrate (368 mg) obtained in Ex. 62 and 10% palladium carbon (0.10 g) in methanol and 1,4-dioxane was stirred at room temperature for 2 hours under a hydrogen atmosphere at 3 atm. Removal of the catalyst and evaporation of the solvent afforded 4-(3-nonyloxycarbonyl-1-indolyl)butyric acid (246 g) as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05530019 |
| Source dataset | uspto-grants-1996_06 |
| ORD ID | ord-18fefe880029477e93f85c894aba0119 |
| Source note | uspto-grants-1996_06 |