HuagongsheHuagongshe Chemistry Print Report · For research reference only
Malic Acid → Methyl (6S)-6,8-dihydroxyoctanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Malic Acid | HCID 525 | — |
| Reactant | (R)-4-Benzyloxy-1,2-butanediol | HCID 10910454 | — |
| Reactant | (2R)-2-[2-(Phenylmethoxy)ethyl]oxirane | HCID 11789783 | — |
| Reactant | 6-Hydroxy-8-(phenylmethoxy)-l-octene | HCID 13717087 | — |
| Product | Methyl (6S)-6,8-dihydroxyoctanoate | HCID 10899438 | — |
Reaction Steps
Chem. Soc. Perkin Trans. I (1988) 9 describes the preparation thereof from the malic acid derivative (S)-4-phenylmethoxy-1,2-butanediol by a multistage reaction sequence with the intermediates (R)-4-phenylmethoxy-1,2-butanediol, (R)-(2-phenylmethoxyethyl)oxirane, 6-hydroxy-8-(phenylmethoxy)-l-octene to give methyl (6S)-6,8-dihydroxyoctanoate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05530143 |
| Source dataset | uspto-grants-1996_06 |
| ORD ID | ord-d36701c2602f45c7a4ffedd68d223a48 |
| Source note | uspto-grants-1996_06 |