HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-2-nitrobenzene → N-[2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)ethyl]-2-nitroaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-2-nitrobenzene | HCID 6945 | — |
| Reactant | 2-(Hexahydro-1H-pyrrolizin-7a-yl)ethanamine | HCID 10796977 | — |
| Product | N-[2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)ethyl]-2-nitroaniline | HCID 178115 | — |
Reaction Steps
The procedures described in Example 12 were repeated except that 1-chloro-2-nitrobenzene (2.04 g, 12.9 mmol) and 5-(2-aminoethyl)-1-azabicyclo[3.3.0]octane (4.00 g, 25.9 mmol) were employed. In this case, the desired compound was obtained as a orange liquid (3.32 g, 98.54%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05530138 |
| Source dataset | uspto-grants-1996_06 |
| ORD ID | ord-93d16f750d3d430f9f19a5a0c842329e |
| Source note | uspto-grants-1996_06 |