HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluorobenzonitrile → 2-[(1-Azabicyclo[3.3.0]octan-5-yl)methylamino]benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluorobenzonitrile | HCID 67855 | — |
| Reactant | (Hexahydro-1H-pyrrolizin-7A-YL)methanamine | HCID 10654304 | — |
| Product | 2-[(1-Azabicyclo[3.3.0]octan-5-yl)methylamino]benzonitrile | HCID 10490308 | — |
Reaction Steps
The procedures described in Example 1 were repeated except that 2-fluorobenzonitrile (671 mg, 5.54 mmol) and 5-aminomethyl-1-azabicyclo[3.3.0]octane (1.94 g, 13.9 mmol) were employed. In this case, the desired compound was obtained as a colorless liquid (1.26 g, 94.2%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05530138 |
| Source dataset | uspto-grants-1996_06 |
| ORD ID | ord-7e00c996ef5b457d8c3f8c8b5a1b6e9c |
| Source note | uspto-grants-1996_06 |