N-[2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)ethyl]-2-nitroaniline → N-[2-(1-Azabicyclo[3.3.0]octan-5-yl)ethyl]-2-nitroaniline(maleate)

Participants

Reaction Steps

A mixture of N-[2-(1-azabicyclo[3.3.0]octan-5-yl)ethyl]-2-nitroaniline (200 mg, 725 μmol) obtained by Example 23 in ethanol (10 Ml) and maleic acid (84.2 mg, 72 μmol) in ethanol (10 ml) was concentrated until its volume becomes 3 ml and left to stand to afford the desired salt (223 mg, 78.6%).

Provenance & Evidence