HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 261016Generated: October 26, 2026
Dimethylformamide → HCID 178508801, compound
https://huagongshe.com/reaction/261016
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 1,5-Diazabicyclo(4.3.0)non-5-ene | HCID 76349 | — |
| Reactant | Dibenzylchlorophosphite | HCID 4372071 | — |
| Reactant | HCID 178513083 | HCID 178513083 | — |
| Product | HCID 178508801 | HCID 178508801 | — |
Reaction Steps
A stirred solution of N-amidino-3,5-diamino-6-chloropyrazinamide (4.6 g., 0.02 mole) and DBN (2.5 g., 0.02 mole) in dimethylformamide (150 ml) is treated with dibenzylchlorophosphite (6.6 g., 0.22 mole) in one portion. The reaction mixture is stirred at 25° C. for 18 hours, filtered and treated with water to precipitate dibenzyl N-[3,5-diamino-6-chloro-pyrazinamido)iminomethyl]phosphoramidate which melts at 187° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04163781 |
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| Source dataset | uspto-grants-1979_08 |
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| ORD ID | ord-313d18eb495148c48f658f4aa9eb3574 |
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| Source note | uspto-grants-1979_08 |
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