HCID 86736598, compound → HCID 333056, compound

HRID 261036Notes

Reaction equation

HRID 261036 reaction equation
C1([C:7]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)([C:13]#[N:14])[CH2:8][CH2:9][C:10](=[O:12])[CH3:11])C=CC=CC=1>S(=O)(=O)(O)O>[C:15]1([CH:7]([C:13]#[N:14])[CH:8]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH2:9][C:10](=[O:12])[CH3:11])[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

3

Reactant 1

HCID 86736598HCID 86736598, compound

Product 1

HCID 333056HCID 333056, compound

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

Thirty grams of 1-2 diphenyl 4-oxo pentane carbonitrile obtained in the course of the first stage are dissolved in the hot state in 270 ml of alcohol at 95° GL. Then 90 ml of concentrated sulphuric acid are added. The reaction mixture is heated under reflux for 6 hours. After cooling it is extracted at least 4 times with 200-100-100-100 ml of CH2Cl2 -- ether (50:50), until almost complete decolorization of the aqueous phase has occured.

Workup

  1. temperatureThe reaction mixture is heated
  2. temperatureunder reflux for 6 hours
  3. temperatureAfter cooling it
  4. extractionis extracted at least 4 times with 200-100-100-100 ml of CH2Cl2 -- ether (50:50), until almost complete decolorization of the aqueous phase

Sources & evidence

ORD record
ord-d0e216453ed84adbbc9af7b1dd81fd33
Source dataset
uspto-grants-1979_08
Patent number
US04163799

Reaction notes

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